Lynne Sinclair, BSc, HBSc., RD

Clinical Dietitian with London Health Sciences Center

Saturday, January 21, 2023

9:45 am – 10:15 am

Nutritional Optimization in Cirrhotic Patients

Presentation Overview

The purpose of this talk will be to provide an update on nutritional optimization in cirrhotic patients. It will highlight contributing factors leading to malnutrition, consequent sarcopenia, simple screening methods, and key features of optimal nutritional therapy for clients with cirrhosis. Included will be a review of the rising prevalence of sarcopenic obesity and nutritional interventions. 

Discussion points will include dietary macronutrients and micronutrients that can affect the relationship between malnutrition and the complications of cirrhosis. Highlighted will be the detrimental effects of oxidized oils and of exceeding the fructose capacity of the liver. The therapeutic benefits of protein prioritisation and of the use of branched-chain amino acid (BCAA) supplementation will be covered as a specific dietary strategy for overcoming anabolic resistance.

The summary will highlight current evidence and recommendations for a dietary framework as part of a comprehensive management strategy for patients with cirrhosis.


Lynne Sinclair has been a clinical dietitian with London Health Sciences Center (LHSC) for 20 years. Her focus is on the nutritional care of adults within hepatology, multi-organ transplantation, home parenteral nutrition, and outpatient gastrointestinal programs.  

Lynne completed her Bachelor of Science in Honors Human Ecology in 2001 at Western University, London, Ontario. She is a member of the College of Dietitians of Ontario, and Dietitians of Canada. 

Lynne’s research and clinical activity centers around the nutritional status and metabolic health of adults requiring liver transplantation. She has been an invited speaker at gastroenterology and liver transplant teaching rounds, local family health teams and The London Liver Update. Lynne’s research interests include; Non-Alcoholic Fatty Liver Disease, metabolic health, End Stage Liver Disease, and frailty in cirrhotic patients awaiting liver transplantation.